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This significantly increases the sensitivity of melanocytes to ferroptosis [72]
Treatment with FOXO4-DRI at 25 M in serum-limited senescent fibroblast and keloid organ culture models promoted apoptosis, decreased G0/G1 phase cells, and induced p53-pS15 nuclear exclusion confirmed by Annexin V-FITC/PI apoptosis assays and TUNEL staining of keloid organ cultures at days 3, 7, and 10
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
Additionally, imatinib, a targeted agent for CD117, inhibits the expression of genes associated with OCSC
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