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However, a meta-analysis on the clinical trial of new hypoglycemic drugs showed that the risk of AKI caused by GLP-1RA was neutral and higher than that of another hypoglycemic drug, sodium-glucose co-transporter 2 inhibitor (SGLT2i) ( Due to the low incidence rate of AKI, the above studies failed to summarize the general characteristics of adverse reactions
Because of this, escalating GLP-1 therapy is no longer just a safety-driven process
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