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Importantly, in mouse xenograft models, 6p produced robust antitumor activity against NSCLC and melanoma, indicating its promise as a selective and effective FASN-targeted cancer therapy for future research and trials (260)
Routes of Administration Subcutaneous (standard and only route): Protocols describe rotating between abdomen, thigh, and upper arm, with abdomen typically providing the most consistent absorption
Blood Flow and Angiogenesis : Preclinical findings indicate stimulation of new blood vessel formation, which may improve oxygen and nutrient delivery to damaged tissues
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