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For patients already taking GLP-1 medications, there is no need for alarm

I saw a patient recently who went from 320 pounds to 180 pounds on Mounjaro, but got so badly constipated they ended up in the emergency room needing to be disimpacted

There are different strategies being investigated for long-term management, such as slowly tapering off the drug or going to alternate forms of dosing, such as every 2-3 weeks instead of weekly