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Survodutide, a GLP-1/glucagon dual agonist, demonstrated approximately 15% weight loss while maintaining euglycemia in a phase II clinical trial [20]

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Serum ACE1 and ACE2 levels and the ACE1/ACE2 ratio are associated with several comorbidities that can worsen COVID-19 severity, including hypertension, type II diabetes, obesity and cardiovascular disease, and in those who smoke 14

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