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The 20252030 patent cliff is the largest in history, covering an estimated $300 billion in branded drug revenue across roughly 200 drugs
They also cross the blood-brain barrier and interact with receptors in your brain that control appetite and satiety
They were discovered in the early 20th century, but their applications in age-related diseases are relatively recent, with a number of studies increasing steadily since the early 2000s
A dedicated kidney study of VA data including more than 89,000 individuals who had COVID-19 noted an increased risk of numerous adverse kidney outcomes 71
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