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to assist dissolution

Over 24 hours at room temperature, NAD + showed tendency to increase by approximately 25% and NADH by 125% from the baseline at collection, while NADP + remained stable and NADPH levels decreased 69% (Supplementary Figure 1a-f)

These mutations cluster near the BoNT/X protease substrate-binding groove, with Thr167Ala positioned close to the scissile bond