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Even assuming a practitioner could prescribe tirzepatide for an extended time period, compounding pharmacies and outsourcing facilities are still restricted by the removal of tirzepatide from FDAs shortage list and would continue to face legal consequences for making and dispensing compounded copies

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Cash Pay Options Manufacturer Direct Programs: Novo Nordisk: $199/month for first two doses, then $349/month Eli Lilly LillyDirect: $299-$499/month depending on dose TrumpRx Platform (Launching Early 2026): Injectable GLP-1s: $350/month initially, dropping to $250 within 2 years Oral GLP-1s (pending FDA approval): $149/month for starting doses GoodRx/Discount Cards: Prices vary by pharmacy and location Typically $900-$1,200/month without manufacturer programs Check current prices at your local Hinsdale pharmacies Cost Comparison: What You'll Actually Pay Ozempic (semaglutide for diabetes): Insurance copay: $25-$100/month Medicare (2026): $50/month Cash (manufacturer direct): $199-$349/month List price: $969/month Wegovy (semaglutide for obesity): Insurance copay: Often not covered Medicare (2026): $50/month Cash (manufacturer direct): $199-$349/month List price: $1,349/month Mounjaro (tirzepatide for diabetes): Insurance copay: $25-$100/month Medicare (2026): $50/month List price: $1,069/month Zepbound (tirzepatide for obesity): Insurance copay: Often not covered Medicare (2026): $50/month Cash (manufacturer direct): $299-$499/month List price: $1,059/month At Well Endocrinology, we help patients navigate insurance coverage, prior authorizations, and manufacturer savings programs to minimize out-of-pocket costs

Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer