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Not an FDA-approved finished drug
This is only a limited clinical observation and not sufficient to infer causality, but it was interesting to later see similar signals emerging in early observational studies
others tolerate morning injections better because daytime activity masks early nausea
Similarly, mice lacking the anti-inflammatory cytokine interleukin 10 (IL-10 -/- mice) spontaneously develop colitis after weaning whereby onset and severity of inflammation are dependent on the microbiota and the genetic background of mice (40), with the 129/SvEv mouse line being more susceptible than C57BL/6 mice
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