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Furthermore, a therapy with dipyridamole, which is now recognized as a potent antioxidant, can prevent the development of early atherosclerotic intimal lesions (which are composed of proliferating smooth muscle cells surrounded by large amounts of collagen, elastic fibers, and glycosaminoglycans) that are observed in hyperhomocyst(e)inemic baboons (Harker et al, 1976)

These CpG sites exhibit different distributions across the genome, and CpG dinucleotide clusters are found at expected frequencies, forming regions known as CpG islands (CGI) (Figure 1)

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