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The impact of the discoveries of the three laureates is huge, as there are more than 500 million diabetic patients and nearly 1 billion individuals with obesity in the world
However, the data presented here in conjunction with clinical data on this mechanism in ALS suggests that it may not be of value to perform clinical studies with GLP-1 agonists in ALS and that resources may be more usefully focussed elsewhere
All authors performed a critical review of the final document
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