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Key findings include enhanced phosphorylation of Src, Caveolin-1, and eNOS, with the vasodilation effect being abolished by nitric oxide inhibitors
At clinical doses under supervision, the most common side effects are mild nausea in the first week (typically resolves by day 7 to 10), injection site reactions (redness, minor swelling, localized soreness lasting 24 hours), and occasional transient fatigue or mild headache in the first few days
The sustained and growing body of research on this compound, spanning multiple countries, research institutions, and animal models, reflects a level of reproducibility that supports continued serious investigation
