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Patients received background therapy with metformin, basal insulin, or both, and were assigned to oral semaglutide at a maximum tolerated dose of 3 mg, 7 mg, or 14 mg once daily, or placebo
IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms
Tirzepatide vs Semaglutide compares another weight loss peptide that has less risk than the already low risk of semagutide
[2] Maturational hyperpigmentation is believed to be associated with metabolic syndrome, similar to facial acanthosis nigricans
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