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Liraglutide and semaglutide are long-acting human GLP-1 analogues with high receptor affinity and sustained receptor occupancy, whereas dulaglutide is a larger fusion molecule conjugated to an IgG4 Fc fragment, resulting in distinct pharmacokinetics and tissue distribution

On weekends and public holidays, lab tests or blood tests at home are accessible

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Ethics declarations Ethics approval and consent to participate The study protocol was conducted according to the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University