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Changes coming to weight loss drug coverage benefits, effective January 1, 2025 Effective January 1, 2025, Independence Blue Cross (IBX) will no longer offer coverage for drugs including glucagon-like peptide-1 receptor antagonist (GLP-1) and non-glucagon-like peptide-1 receptor antagonist (non-GLP-1) indicated for and prescribed solely for weight loss in the absence of other FDA-approved clinical indications