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Some clinicians prescribe lower doses of 15 mg or 8 mg for patients who experience side effects at the full dose
A phase 3 study conducted on patients with T2DM has shown that tirzepatide improves HbA1c levels at all doses (515 mg)
The effect of varying albumin levels on unbound fraction of pazopanib in patient plasma would need to be further investigated using a larger sample size with wider albumin range for it to be meaningful (Toh et al., 2020)
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