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Coverage policies vary widely: a KFF 2025 employer survey found 43% of firms with 5,000+ workers now cover GLP-1 weight-loss drugs (up from 28% in 2024) ( [6] ), yet many patient advocacy reports and journalists note patients cutting doses or resorting to unapproved sources due to cost ( [4] ) ( [7] )

For those working with compounded formulations, proper handling is essential

Research Applications and Legal Compliance According to early findings published on PubMed , retatrutide has demonstrated promising metabolic effects in controlled research settings

Doubling up on B6 from both the compound and oral supplements is unnecessary and, at very high levels over extended periods, can actually cause peripheral neuropathy, the very symptom that B6 deficiency also causes