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It's one of the fundamental mechanisms of aging
When glutathione levels drop, the immune system effectively "loses its brakes," allowing for the overproduction of pro-inflammatory cytokines like Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-)
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Regulation of hypoxia-inducible factor 1 is mediated by an O 2 -dependent degradation domain via the ubiquitin-proteasome pathway
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