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TGF- Pathway Activation Organizes the actin cytoskeleton in fibroblasts while restoring collagen contraction and remodeling capacity, essential for proper wound closure
VEGFR2 activation angiogenesis newly formed blood vessels at the injured site supply of oxygen, nutrients, immune cells
2017;31:737754.e6
Reviewing previous IBD treatment response: If a biologic or advanced IBD treatment has not worked as expected, it may be appropriate to review treatment history, disease activity, drug levels, antibodies, timing of response and whether symptoms are due to inflammation or an overlapping condition
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