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303.1 Understanding the experience of people living with amyotrophic lateral sclerosis: a qualitative study and conceptual model informed by patients, caregivers, and clinicians William Nowell 1 , Nadine McGale 2 , Oren Levy 1 , Sarah Wilding 2 , Phoebe Heinrich 2 , Nick Patel 1 , Jinsy Andrews 3 , Diana Rofail 1 1 Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA, 2 Modus Outcomes, Cambridge, Massachusetts, USA, 3 Department of Neurology, Colombia University, New York, USA Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :303.1 Aims This qualitative study aimed to (1) explore the experience of living with amyotrophic lateral sclerosis (ALS) through interviews with patients, caregivers, and clinicians, and (2) develop a conceptual model for this rare, progressive disease

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Some people may lose more or less depending on their metabolism, starting weight, and how strictly they follow personal care guidance