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This is in contrast to spironolactone a steroidal mineralocorticoid receptor antagonist with well-characterised anti-androgenic properties which is an established cause of gynaecomastia through a distinct and unrelated mechanism
doi: 10.1016/S0140-6736(19)31149-3 9 DaviesMJDAlessioDAFradkinJKernanWNMathieuCMingroneGet al
Adipose tissue plays a role in hormone metabolism, and substantial changes in body composition may influence testosterone and oestrogen levels, potentially affecting libido in both men and women
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