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If Phase III trials are successful, Novo Nordisk may seek FDA and EMA approval in the next few years
Firsocostat and cilofexor are orally administered inhibitors that are used to target ACC in clinical drug development for the treatment of steatohepatitis associated with metabolic dysfunction (144)
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however, well-designed clinical trials are required to confirm its efficacy, elucidate mechanisms, and establish optimal dosing strategies
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