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Practical strategies to minimize hypotension risk include: Adequate hydration: Maintain consistent fluid intake throughout the day based on individual needs and medical conditions (consult your provider for personalized recommendations, especially if you have heart failure or kidney disease) Gradual position changes: Rise slowly from lying to sitting, then sitting to standing, pausing between transitions Dietary sodium: Unless contraindicated, maintain adequate sodium intake as directed by your healthcare provider Compression stockings: Knee-high or thigh-high compression garments (20-30 mmHg) may help prevent blood pooling

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The targeted deletion of HIF-1 in HCC cells resulted in reduced tumor growth, increased apoptosis, and suppressed angiogenesis in both in vitro and in vivo models (215)