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Potential side effects are often minimal compared to other peptides, partially because ipamorelin specifically stimulates growth hormone without significantly affecting other hormones

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Compared to monotherapy, combination therapy resulted in a greater reduction in glycated haemoglobin (HbA1c), body weight, fasting plasma glucose (FPG), 2 h postprandial glucose (2 h PG), systolic blood pressure (SBP), body mass index (BMI) and low-density lipoprotein cholesterol (LDL-C)

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However, they come with a catch

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In a more detailed study, morroniside enhanced IL-10 and -endorphin gene expression in the spinal lumbar enlargements and cultured microglia of neuropathic rats [39]

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