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Side Effects: Cardiac arrhythmias Dyspnea Nausea Vomiting Headache Pharmacokinetics: Dopamines onset of action occurs within five minutes of intravenous administration, and with dopamines plasma half-life of about two minutes, the duration of action is less than ten minutes

The GHK sequence also appears within the alpha-2(I) chain of type I collagen, leading to the hypothesis that collagen degradation at wound sites releases GHK fragments that then bind copper and signal for new collagen production, creating a self-repair feedback loop

doi: 10.3389/fphar.2023.1303844 Received 28 September 2023 Accepted 30 November 2023 Published 11 December 2023 Volume 14 - 2023 Edited by Alessio Squassina, University of Cagliari, Italy Reviewed by Michele Mazzanti, University of Milan, Italy Yashmin Choudhury, Assam University, India Updates Copyright 2023 Greco, Coperchini, Croce, Magri, Teliti and Rotondi