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Using a yeast interaction network (The Cell Map 27 ), we identified GSH1 and GSH2 (yeast glutamylcysteine ligase and glutathione synthetase, respectively) as two of the highest scoring synthetic lethal interactions of mtm1, the S.cereviase ortholog for SLC25A39 (p-value=2.78E-28 (GSH1)
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Last updated: October 29, 2025
Combining Retatrutide with other weight loss medications is not generally recommended without medical supervision due to potential interactions and increased risk of side effects
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