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-TrCP is a substrate receptor of the Skp1-Cul1-Rbx1/Roc1 ubiquitin ligase complex and therefore targets Nrf2 for ubiquitination and proteasomal degradation
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A diuretic had been reduced during a hospitalization, but the pharmacy's auto-refill kept sending the original dose, the bottle arrived in the mail, and the patient resumed it because that's what the label said to do
Manufacturer coupons and savings programs sometimes reduce out-of-pocket costs for insured patients, but these programs often exclude government payers
