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Retatrutide has the highest overall adverse event burden, primarily because of the dysesthesia issue
While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables
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This hindrance in timely identification is compounded by individuals frequent oversight of symptoms and the potential misinterpretation by primary care physicians [34]
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