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[16] [17] Synthesis [edit] Biosynthesis [edit] Glutamate is primarily synthesized from -ketoglutarate, an intermediate of the TCA cycle, through either transamination or reductive amination
This is done in an effort to decrease the pain secondary to ischemia and also the postulated damage to tissue due to the free radicals
This makes them more susceptible to irritation, especially from the potent exfoliating power of glycolic acid
But for people with active cancer, a prior cancer diagnosis, or ongoing cancer treatment, NAC is something to discuss with an oncologist or healthcare provider before use
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