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Clinical evidence shows that patients initiating therapy at 0.25 mg weekly often experience appetite suppression within days, leading to reduced calorie intake without conscious dietary restriction

Regular maintenance sessions are necessary to sustain the effects, with the frequency customised based on individual needs and how well the treatment works [4]

All parameters were successfully estimated (relative standard error 11%) in the final model using data from the nine clinical trials (Table 4)

Splitting doses Some researchers experiment with splitting their weekly dose into two smaller injections given 3 to 4 days apart