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Moreover, this segment will also give a brief overview of the existing treatment paradigm of the target indications

Any changes in urine appearance are typically indirect, resulting from the medication's gastrointestinal side effects that may affect hydration status

12 13 Therapeutic Potential : In sleep medicine, modulating orexin pathways is a promising strategy for addressing conditions such as insomnia and excessive wakefulness

The natriuretic effect of GLP-1RAs may also be partially attributed to a reduction of the activity of the reninangiotensinaldosterone system, as in clinical studies, GLP-1 and GLP-1RAs have been found to lower circulating angiotensin II levels by approximately 20% [24, 25]