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Translocation of xenobiotic glutathione conjugates in roots of barley (Hordeum vulgare)
doi: 10.3389/fnut.2022.1067647 Received 12 October 2022 Accepted 07 November 2022 Published 24 November 2022 Volume 9 - 2022 Edited by Evelyn Frias-Toral, Catholic University of Santiago de Guayaquil, Ecuador Reviewed by Beatriz Quintero, Universidad de Los Andes, Venezuela
La sintesi parte da 6-N-trimetillisina (TML) , derivata dalla metilazione della lisina, e procede attraverso passaggi enzimatici che richiedono vitamina C e ferro (idrossilazione), vitamina B6 (reazione con fosfato piridossale) e reazioni NAD+-dipendenti fino alla formazione di L-carnitina
Achieving glycaemic control without weight gain, hypoglycaemia, or gastrointestinal adverse events in type 2 diabetes in the SUSTAIN clinical trial programme
