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NADPH oxidase 2 (NOX2) is the key enzyme responsible for the cellular ROS production by using superoxide radicals (O 2 -) as precursor molecule [59]
Better understanding of the cellular and molecular pathways driving APAP-induced liver injury is key to find novel biomarkers, therapeutic targets, and unrecognized drugs which may sensitize patients to APAP-induced hepatotoxicity
Derived from Thymosin Beta-4, it plays a role in cellular migration and regeneration, essentially helping the body mobilize the resources it needs to heal
J., Lang, H
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