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A study shows that targeting WNT2 secreted by tumor-associated fibroblasts can restore dendritic cell-mediated antitumor immunity, suggesting its important role in anti-tumor immunity ( Notably, we also found a negatively correlation between GLP-1 signaling score and TMB/MSI in LIHC, LUAD, BLCA, HNSC, STAD, BLCA, COAD and so on, demonstrating there may be high microsatellite instability or tumor mutation burden in these tumors, thus antitumor immunity is more likely to be activated

IV glutathione is one such tool, useful in select cases, not all

Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JFE, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB

B 9 , 11631173 (2019)