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Their absorption is generally not significantly affected by delayed gastric emptying, and they do not share metabolic pathways with semaglutide

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Exenatide, dapagliflozin, or phentermine/topiramate differentially affect metabolic profiles in polycystic ovary syndrome

euphoria , sedation , muscle relaxation, hypotension , bradycardia , & decreased perception of pain It may also affect 1 adrenergic, histamine, serotonin, and opioid receptors (Hoffman et al, 2001