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The most frequently reported side effects of Wegovy are gastrointestinal in nature, including nausea (very common, 1/10), vomiting, diarrhoea, constipation, and abdominal pain
Nanomedicine 2008
Additionally, by pre-treating with the GRP receptor antagonist RC-3095, they found that GRP also plays a partial role in metformin-induced GLP-1 secretion
We have previously demonstrated that the lack of TrkB signalling in cholecystokinin (CCK)-GABAergic neurons leads to glucocorticoid resistance
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