Medical Considerations: Semaglutide or Tirzepatide, including micro-dose programs, cannot be prescribed and should not be purchased by individuals with a BMI under 25 (or under 20 for micro-dosing), an eating disorder, diabetes, gallbladder disease, history of drug or alcohol abuse, recent bariatric surgery, pancreatitis, medullary thyroid cancer or a family history of it, diabetic retinopathy, multiple endocrine neoplasia type 2, or those who are pregnant, breastfeeding, or planning to become pregnant
Diabetes Care 36 , 24152422 (2013)
Personalized Treatment With Precision Peptide Genetic Testing The PlexusDx Precision Peptide Genetic Test analyzes GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) variants that relate to GLP-1 and related signaling pathways
At study entry, patients in study 1 were not treated with oral antihyperglycemic agents