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Acknowledgements This work was supported by research grants from the National Key Research and Development Program of China (2016YFA0100501), the Chinese National 973 Program (2012CB517502), the National Natural Sciences Foundation of China (81400798, 81400767, 81401142, 81270858, and 81570692), and the Beijing Natural Sciences Foundation of China (7163233)
Studies have shown that DSIP modifies opioid tolerance and dependence in animal models and possesses its own analgesic activity independent of classical opioid receptors
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Peptide therapy may be combined with other regenerative treatments as part of a comprehensive recovery strategy
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