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DNA adducts are formed through binding of compounds such as acetaldehyde and modified bases, which are known for their ability to induce mutations in the DNA that facilitates activation of oncogenes, through inactivation of tumor suppressor genes, and through immune response due to recognition of proteins bound to foreign structures by the immune system
Direct delivery into circulation allows the peptide to reach target tissues without the absorption loss associated with oral forms
Davies KJ, Sevanian A, Muakkassah-Kelly SF, Hochstein P
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