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GLP-1 weight loss injections are clinically proven and approved for weight loss, while patches are not

Its pathway to NHS availability will depend on the successful completion of Phase 3 TRIUMPH trials, followed by a marketing authorisation application to the MHRA (the UK's independent medicines regulator) and potentially the EMA for European markets

[29, 30, 31] Risk factors: Diabetes (especially in combination with SGLT2 inhibitors use) Reduced oral intake and severe GI symptoms Dehydration Presentation: Nausea, vomiting, abdominal pain Anion gap metabolic acidosis Elevated ketones Normal or mildly elevated glucose Key point: EDKA has not been observed in non-diabetic patients in large cohort data

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