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Furthermore, the preclinical works which unravel the effects of GLP-1 in ocular dynamics and the preclinical literature regarding GLP-1RA use in the management of several neuro-ophthalmic conditions, including diabetic retinopathy (DR), glaucoma, and idiopathic intracranial hypertension (IIH) are discussed

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Wegovy is an FDA-approved medication for chronic weight management, cardiovascular risk reduction and to treat moderate-to-advanced liver scarring as of August 2025

Cagrilintide adds amylin signaling, but there is no direct trial comparing the combination with retatrutide alone