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While patients with minimal alcohol use (up to 20/30 g/d in women/men) were enrolled in the ESSENCE trial, those with higher alcohol consumption [ie, in the MetALD (metabolic dysfunction and alcohol-associated liver disease) range] were excluded
Detrimental skin changes also play an important role in facial aging
GLUL is highly expressed in HCC cells, and it has been demonstrated that this mediates EMT, thus promoting HCC cell invasion and metastasis [65]
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