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Finally, we expressed H188 in HEK293 cells by viral transduction to demonstrate that soluble adenylyl cyclase (sAC) activity could be monitored in FRET assays that compared wild-type (WT) HEK293 cells or HEK293-sAC cells treated with IBMX in the presence or absence of the selective sAC inhibitor LRE1 (Fig

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Blood tests may show increased bilirubin, alkaline phosphatase, GGT, ALT, AST, or white blood cells when biliary obstruction or inflammation is present