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Description

Therapeutically, these cells can be further potentiated using agents that intensify iron release (e.g., NCOA4 activators), enhance ACSL4-mediated PUFA incorporation, or inhibit GPX4-stabilizing pathways (106)

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The "Ac-" prefix is a small chemical modification added to the beginning of the peptide

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It has been the subject of hundreds of published preclinical studies examining its effects across multiple tissue types

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