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Tirzepatide once weekly for the treatment of obesity
Two weeks following the final immunization, we employed the ex vivo Mycobacterial Growth Inhibition Assay (MGIA) as a surrogate of protective efficacy ( Figure 3 )
It fuels the electron transport chain, activates repair enzymes called sirtuins, and declines sharply with age
It was originally studied in the context of gastrointestinal healing, where the parent protein appears to play a role in protecting the gut lining
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