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Based on clinical tolerance studies, the recommended maximum daily intake is 0.9 g/kg body weight and should be taken in multiple doses
A 10-year longitudinal follow-up of a retrospective cohort comprising 159 patients with PCOS treated with metformin reported that the total testosterone and androstenedione decreased to 15.4 47.9% and 11.3 46.4% within first year, with further decrease in total testosterone and androstenedione to 37.8 61.8 and 24.8 40.5% at the fifth year of the follow-up (38, 39)
Pink Bariatric Gelatin (Sugar-Free Jello Hack) Replace half the hot water with sugar-free strawberry or raspberry gelatin mix (one-quarter of a standard box)
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