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Research has examined NNMT inhibition and its downstream effects on cellular NAD+ salvage, methylation balance and adipocyte energy metabolism, with preclinical work exploring roles in lipid handling and metabolic regulation
A 2023 clinical research review noted that GLP-1 receptor agonist studies have shown average body weight reductions of 15% or more over extended trial periods, which is part of why this compound class has attracted significant research attention
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