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And the doctor who prescribed it would refute the lack of data, saying the absence of evidence is not evidence of absence, and that his patients are deriving substantial benefit without side effects

[1] [2] There are pen-based workarounds, staying at the lowest strengths long term or spacing doses further apart, and we've covered how providers handle those in the Wegovy and Zepbound guides

For GLP-1 medications like semaglutide or tirzepatide, legitimate examples of a documented clinical difference might include: A patients allergy to an excipient (e.g., phenol or sodium chloride) in the commercial formulation