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Oxidative stress occurs when the body is overwhelmed by an excess of harmful molecules called free radicals, which it struggles to neutralise
It is highly suitable for extended experimental protocols and dose-response studies
Both DPP-4 inhibitors and GLP-1 RAs have demonstrated safety in robust cardiovascular outcome trials, while several GLP-1 RAs have been shown to significantly reduce the risk of major adverse cardiovascular events in persons with T2DM with pre-existing cardiovascular disease (CVD)
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