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doi:10.1177/08971900221101761 Tashkin DP, Lipworth B, Brattsand R
You discover that what seemed like an inevitable consequence of the medication was actually a constellation of fixable problems, each with its own solution
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In TRIUMPH-4, a 68 week trial in adults with obesity or overweight plus knee osteoarthritis, the 12 mg arm averaged 28.7% body weight loss using the efficacy estimand, with the 9 mg arm at 26.4%
It stimulates the pituitary gland to release growth hormone (GH), and GH itself has a mild, transient diabetogenic effect, meaning it can temporarily raise blood sugar and decrease insulin sensitivity
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